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Assemble your dream team to fight the germs!
✓ Set the body up for success to fortify your defenses against illness*
✓ Support your immune cells’ natural ability to keep you healthy*
✓ Bolster the body’s natural antioxidant defenses*
✓ Decrease inflammation, so your immune system can focus on foreign invaders*
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This supplement blends the best potent, immune-supporting minerals, vitamins, and botanicals. Your child will love this tasty, lemon-berry flavored lozenge, which is sweetened naturally with stevia, xylitol, and honey powder. The lozenge allows the zinc to come into direct contact with the throat to inhibit viruses. This is one of the most powerful immune supplements available, which can be given to your child year-round to boost their immune system.*
Zinc is an essential mineral that plays a fundamental role in many physiological processes, including immune system function. This supplement contains two easily absorbed forms of zinc citrate and zinc gluconate. That means they can go to work quickly to support your child’s immune system.*
Enhanced Immune Response: Zinc supports the development and function of immune cells like macrophages, neutrophils, and natural killer cells.*1
Antiviral Properties: Zinc has been shown to inhibit the replication of certain viruses, potentially reducing the severity and duration of viral infections.*23
Direct Impact on Cold Viruses: Some studies indicate that if zinc is taken within 24 hours of the onset of cold symptoms, it can reduce the duration and severity of the cold and related symptoms, including sore throat, nasal congestion, and cough. Additionally, research suggests that zinc can directly inhibit the rhinovirus, which is responsible for many cases of the common cold.*45
Wound Healing: Zinc plays a crucial role in skin integrity and wound healing.This property can be beneficial in the context of skin issues that may arise from constant nose blowing or other cold-related symptoms.*6
Thymus Health: The thymus is an organ responsible for T-cell maturation. Zinc is essential for its function, supporting adaptive immunity.*7
BONUS: In addition, zinc is involved in other areas of health including brain function8, growth9, and detoxifying heavy metals10—to name just a few.*11
1 Prasad, A. S. (2008). Zinc in human health: effect of zinc on immune cells. *Molecular medicine*, 14(5-6), 353-357.
2 Read, S. A., Obeid, S., Ahlenstiel, C., & Ahlenstiel, G. (2019). The role of zinc in antiviral immunity. *Advances in Nutrition*, 10(4), 696-710.
3 Suara, R. O., & Crowe Jr, J. E. (2004). Effect of zinc salts on respiratory syncytial virus replication. *Antimicrobial agents and chemotherapy*, 48(3),783-790.
4 Singh, M., & Das, R. R. (2013). Zinc for the common cold. *The Cochrane database of systematic reviews*, (6), CD001364.
5 Hemilä, H. (2017). Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage. *JRSM open*, 8(5), 2054270417694291.
6 Lansdown,A. B. G., Mirastschijski, U., Stubbs, N., Scanlon, E., & Ågren, M. S.(2007). Zinc in wound healing: theoretical, experimental, and clinical aspects.*Wound Repair and Regeneration*, 15(1), 2-16.
7 Fraker, P. J., King, L. E., Laakko, T., & Vollmer, T. L.(2000). The dynamic link between the integrity of the immune system and zinc status. The Journal of Nutrition, 130(5S Suppl), 1399S-1406S.
8 Takeda, A. (2000). Movement of zinc and its functional significance in the brain. BrainResearch Reviews, 34(3), 137-148.
9 Brown, K. H., Peerson, J. M., Rivera, J., & Allen, L. H.(2002). Effect of supplemental zinc on the growth and serum zinc concentrations of prepubertal children: a meta-analysis of randomized controlled trials. TheAmerican Journal of Clinical Nutrition, 75(6), 1062-1071.
10 Wang,X., Zhou, B., & Sun, L. (2010). Bioaccumulation of heavy metals in organs of freshwater fish Cyprinus carpio (Common carp) and its potential risk to human health. Asian Journal of Chemistry, 22(8), 6017.
11 Prasad, A. S. (2003). Zinc deficiency. BMJ: British MedicalJournal, 326(7386), 409.
Vitamin D is an immune system superstar that can keep your child healthy even in the face of powerful immune challenges.* Its receptors are found in every cell of the immune system.* Vitamin D keeps immune cells working their best.*
Regulation of Immune Cells: Vitamin D helps regulate the function ofT-cells, B-cells, and dendritic cells, all of which play essential roles in the immune response.*1
Reduced Risk of Infections: Adequate vitamin D levels have been associated with a decreased risk of respiratory tract infections, including colds.*2
Symptom Severity: Some studies suggest that adequate vitamin D levels may decrease the severity and duration of cold symptoms.*3
Anti-inflammatory Properties: Vitamin D can reduce the release of pro-inflammatory cytokines, thereby preventing excessive inflammation that can be damaging during infections.*4
Production of Antimicrobial Peptides: Vitamin D stimulates the production of cathelicid in and defensins, which have antimicrobial properties and can combat pathogens.*5
Enhanced Barrier Function: Vitamin D supports the integrity of epithelial barriers, like those in the lungs and gut, potentially reducing susceptibility to infections.*6
Improved Antibiotic Effects: In certain cases, vitamin D can enhance the pathogen-killing effect of antibiotics, making them more effective.*7
1 Aranow, C. (2011). Vitamin D and the immune system. *Journal of investigative medicine*, 59(6),881-886.
2 Martineau, A. R., Jolliffe, D. A.,Hooper, R. L., Greenberg, L., Aloia, J. F., Bergman, P., ... & Camargo, C.A. (2017). Vitamin D supplementation to prevent acute respiratory tractinfections: systematic review and meta-analysis of individual participant data.*BMJ*,356, i6583.
3 Martineau, A. R., Jolliffe, D. A., Hooper, R. L., Greenberg, L., Aloia, J. F., Bergman, P., ... & Camargo, C. A. (2017). Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. *BMJ*,356, i6583.
4 Kongsbak, M., Levring, T. B., Geisler, C., & von Essen, M. R. (2013). The vitamin d receptor and T cell function. *Frontiers in immunology*, 4, 148.
5 Gombart, A.F., Borregaard, N., & Koeffler, H. P. (2005). Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1, 25-dihydroxyvitamin D3. *The FASEB Journal*, 19(9), 1067-1077.
6 Mora, J. R., Iwata, M., & Von Andrian, U. H. (2008). Vitamin effects on the immune system: vitamins A and D take centre stage. *Nature Reviews Immunology*,8(9), 685-698.
7 Yuk, J. M., Shin, D. M., Lee, H. M., Yang, C. S., Jin, H. S., Kim,K. K., ... & Jo, E. K. (2009). Vitamin D3 induces autophagy in humanmonocytes/macrophages via cathelicidin. *Cellhost & microbe*, 6(3), 231-243.
Elderberry (Sambucus nigra) has been used traditionally for various ailments, and modern research has begun to shed light on its benefits, particularly for the immune system.*
Antiviral Properties: Elderberry contains compounds that have demonstrated antiviral activity against influenza and certain strains of respiratory viruses.*12
Immune System Boost: The bioflavonoids in elderberries can stimulate the immune system, making it more effective at fighting off pathogens.*3
Rich in Antioxidants: Elderberries are high in antioxidants, particularly anthocyanins, which can help counteract oxidative stress in the body.*4
Anti-inflammatory Effects: Elderberry has anti-inflammatory properties which can help reduce symptoms associated with colds and flu.*5
Rich in Vitamin C: Elderberry is a natural source of vitamin C, an essential nutrient known to boost the immune system.*6
1 Zakay-Rones, Z., Thom, E., Wollan, T., & Wadstein, J. (2004).Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. *Journal of International Medical Research*,32(2), 132-140.
2 Krawitz,C., Mraheil, M. A., Stein, M., Imirzalioglu, C., Domann, E., Pleschka, S.,& Hain, T. (2011). Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses. *BMCComplementary and Alternative Medicine*,11(1), 16.
3 Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. *Complementary Therapies in Medicine*, 42, 361-365.
4 Viapiana, A., & Wesolowski, M. (2017). The phenolic contents and antioxidant activities of infusions of Sambucus nigra L. *PlantFoods for Human Nutrition*, 72(1),82-87.
5 Ulbricht, C., Basch, E., Cheung, L., Goldberg, H., Hammerness, P.,Isaac, R., ... & Wortley, J. (2014). An evidence-based systematic review of elderberry and elderflower (Sambucus nigra) by the Natural Standard ResearchCollaboration. *Journal of DietarySupplements*, 11(1), 80-120.
6 Duymuş,H. G., Göger, F., & Başer, K. H. C. (2013). In vitro antioxidant properties and anthocyanin compositions of elderberry extracts. *Food chemistry*, 141(2),948-955.
Suggested Use: As a dietary supplement, children 4 or older take 1 (1.4 g) scoop daily, or as directed by your healthcare practitioner.
Storage: Keep out of reach of children. Store in a cool, dry place.
WARNING: If your child has any health conditions, consult your healthcare practitioner before taking this product
Vitamin C, also known as ascorbic acid, is a vital nutrient for various bodily functions, including super-charging the immune system.* Supplementing with vitamin C year-round ensures that your child will get enough of this vitamin and all of its immune-boosting health benefits.* Our tasty, naturally cherry-flavored tablets combine Vitamin C and bioflavonoids to support children’s immune health, iron absorption, and overall health.*
Immune Cell Enhancement: Vitamin C supports the production and proper function of white blood cells, including neutrophils, lymphocytes, and phagocytes, which help defend against infections.*1
Fights the Common Cold and Viral Illness: Some studies have shown that vitamin C can reduce the duration and severity of cold symptoms.*2
Antioxidant Properties: Vitamin C acts as a powerful antioxidant, protecting the body against free radicals and reducing oxidative stress, which can be detrimental to immune function.*3
Skin Health Support: Vitamin C supports skin integrity, aiding in the skin's role as a barrier against pathogens and environmental exposures.*4
Wound Healing: Vitamin C is essential for collagen synthesis, which is crucial for wound healing and tissue repair.*5
Supporting Other Immune Components: Vitamin C enhances the body's ability to absorb iron from plant-based foods, which is necessary for optimal immune function.*6
Beyond immune health: Vitamin C has another critical role to play. Your child’s body needs it in order to absorb iron.7 Healthy levels of this mineral are associated with attention span, mood, and getting enough sleep.8 While giving higher doses of iron to kids can lead to an upset tummy, lower doses of iron together with vitamin C can boost absorption of the mineral and may help lower the instance of stomach upset.*9
1 Wintergerst,E. S., Maggini, S., & Hornig, D. H. (2006). Immune-enhancing role of vitamin C and zinc and effect on clinical conditions. *Annals of Nutrition & Metabolism*, 50(2), 85-94.
2 Hemilä, H., & Chalker, E.(2013). Vitamin C for preventing and treating the common cold. *Cochrane Database of Systematic Reviews*, (1).
3 Carr, A. C.,& Maggini, S. (2017). Vitamin C and immune function. *Nutrients*,9(11), 1211.
4 Pullar,J. M., Carr, A. C., & Vissers, M. C. (2017). The roles of vitamin C in skin health. *Nutrients*, 9(8), 866.
5 Mohammed, B.M., Fisher, B. J., Huynh, Q. K., Wijesinghe, D. S., Chalfant, C. E., Brophy, D.F., ... & Natarajan, R. (2013). Resolution of sterile inflammation: role for vitamin C. *Mediators ofInflammation*, 2013.
6 Maggini,S., Wintergerst, E. S., Beveridge, S., & Hornig, D. H. (2007). Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. *British Journal of Nutrition*,98(S1), S29-S35.
7 Hallberg, L., & Hulthén, L. (2000). Prediction of dietary iron absorption: an algorithm for calculating absorption and bioavailability of dietary iron. The American Journal of Clinical Nutrition, 71(5), 1147-1160.
8 Lozoff, B.,Jimenez, E., & Smith, J. B. (2006). Double burden of iron deficiency in infancy and low socioeconomic status: a longitudinal analysis of cognitive tests cores to age 19 years. Archives of Pediatrics & Adolescent Medicine, 160(11),1108-1113.
9 Miret, S., Simpson, R. J., & McKie, A. T. (2003). Physiology and molecular biology of dietary iron absorption. Annual Review of Nutrition, 23(1), 283-301.
Suggested Use: As a dietary supplement, children 4 or older take 1 (1.4 g) scoop daily, or as directed by your healthcare practitioner.
Storage: Keep out of reach of children. Store in a cool, dry place.
WARNING: If your child has any health conditions, consult your healthcare practitioner before taking this product
Suggested Use: As a dietary supplement, children 4 or older take 1 (1.4 g) scoop daily, or as directed by your healthcare practitioner.
Storage: Keep out of reach of children. Store in a cool, dry place.
WARNING: If your child has any health conditions, consult your healthcare practitioner before taking this product
✓ Step-by-step instructions on how and when to introduce each supplement
✓ Easy supplement administration tips
✓ How to make supplements fun for kids
✓ Simple, healthy recipes to mix in supplement powders and liquids
✓ Reminder schedule for your smartphone
✓ The science-based behind each supplement
✓ Step-by-step instructions on when to start each supplement
✓ Supplement administration tips
✓ Reminder schedule for your smartphone
✓ The science base behind each supplement
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